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Transcorneal Electrical Stimulation Therapy May Have a Stabilization Effect on Multifocal Electroretinography for Patients with Retinitis Pigmentosa

Dizdar Yigit and co-workers aimed to assesses the effects of transcorneal electrical stimulation on several objective and subjective measures of visual function in retinitis...

Differences in long-term progression of atrophy between neovascular and non-neovascular age-related macular degeneration

Purpose: To compare enlargement rates over 5 years of follow-up in geographic atrophy (GA) versus macular atrophy (MA) associated with macular neovascularization (MNV). Design:...

51. Choroideremia

Medical History: A 39-year-old male patient presented with complaint of gradually progressive loss of night vision. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best...

Question of the Month-May 2022

Optic coherence tomography, infrared reflectance and OCT-angiography images of a 35-year-old male patient, complaining visual loss in the left eye for 5 years, are shown. It is known that his father also had same...

No difference in the incidence of age-related macular degeneration between statin users and nonusers

Age-related macular degeneration shares many of the same risk factors with atherosclerosis. There is a postulated role of lipid-lowering agents in preventing age-related macular degeneration. Through this meta-analysis, Eshtiaghi and co-workers demonstrate no significant...

Efficacy of Half-Dose Photodynamic Therapy Versus High-Density Subthreshold Micropulse Laser for Treating Pigment Epithelial Detachments in Chronic Central Serous Chorioretinopathy

Purpose: Comparing the effect of half-dose photodynamic therapy and high-density subthreshold micropulse laser treatment on retinal pigment epithelial detachments (PEDs) in chronic central serous chorioretinopathy. Methods: This study included data from the PLACE trial, a...

50. Choroidal Neovascularization Associated with Angioid Streaks in Pseudoxanthoma Elasticum

Medical History: A 27-year-old female patient presented with complaint of blurry vision in the right eye for the past 3 weeks.   Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Small yellowish papules coalescing into...

The Pearl Necklace Sign-April 2022

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, describe the OCT finding in a patient with disciform scar and cystoid macular degeneration was asked. The...

Hyper-reflective oval deposits – March 2022

The OCT image of a patient who developed posterior uveitis is shown. Could you determine the diagnosis and describe the OCT findings indicated by arrows of this patient? Thanks to everyone who showed interest in...

Subjects with central serous chorioretinopathy are at increased risk of exudative age-related macular degeneration

Lee and co-workers aimed to estimate the risk of incident age-related macular degeneration (AMD) in patients with central serous chorioretinopathy (CSC). During a recent 5-year study period, 36,053 patients were identified as having incident...

Predictors of Retinal Pigment Epithelium Tear Development After Treatment for Neovascular Age-Related Macular Degeneration Usıng Swept-Source Optical Coherence Tomography Angiography

Purpose: To investigate the predictors of retinal pigment epithelium (RPE) tear development after treatment for neovascular age-related macular degeneration (AMD) using swept-source optical coherence tomography angiography (OCTA). Methods: This prospective study included 152 treatment-naïve eyes...

49. Vascularized serous pigment epithelial detachment in age-related macular degeneration

Medical History: A 75-year-old female patient presented with complaint of gradually progressive blurring of vision in the left eye for the past 3 months.   Diabetes mellitus (+) Systemic hypertension (+)   Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected...

Retinal age as a predictive biomarker for mortality risk

Zhu and co-workers aimed to develop a deep learning (DL) model that predicts age from fundus images (retinal age) and to investigate the association between retinal age gap (retinal age predicted by deep learning...

Hyperreflective foci as important prognostic indicators of progression of retınitis pigmentosa

Purpose: To investigate the presence and clinical relevance of hyperreflective foci (HRFs) in retinitis pigmentosa. Methods: Seventy seven retinitis pigmentosa cases were retrospectively reviewed. The 10-mm wide cross-line macular scans in optical coherence tomography were acquired. Hyperreflective...

Nebulous Pattern Vitritis-February 2022

The OCT image of a patient who developed cytomegalovirus retinitis is shown. Could you describe the OCT findings indicated by asterisk and arrows of this patient? Thanks to everyone who showed interest in the section...

Alport Syndrome-January 2022

Looking at the optical coherence tomography images and infrared reflectance images, could you tell the diagnosis in this 42-year-old female patient with the diagnosis of chronic kidney disease? Thanks to everyone who showed interest in...

47. Very Late Onset Irvine-Gass Syndrome

Medical History: A 68-year-old female patient presented with complaint of blurry vision in her left eye for 2 months. In her history; 8 years ago she had bilateral cataract surgery. Diabetes mellitus  (+) Systemic hypertension (+) Family history...

Intraretinal fluid may be associated with good visual acuity in Type 3 macular neovascularization

Sharma and co-workers aimed to analyze the effect of fluid on visual acuity in cases of Type 3 macular neovascularization. This multicentric, retrospective cohort study included eyes with treatment-naïve Type 3 macular neovascularization. Analysis...

Peripapillary pachychoroid syndrome: New Insights

Purpose: Available literature on peripapillary pachychoroid syndrome (PPS) is very limited. The purpose of this study is to evaluate features of PPS using multimodal imaging and shed further light on this entity. Methods: This is...

Macular Hole Closure Without Endotamponade Application

Stopa and co-workers describe an alternative vitreoretinal technique that allows for the macular hole closure without filling the vitreous cavity with gas. The patients underwent the formation of viscoelastic-assisted temporal internal limiting membrane flap...

Correlation between focal choroidal excavation and underlying retinochoroidal disease: A pathological hypothesis from clinical observation

Purpose: To evaluate focal choroidal excavation (FCE) in eyes with various diseases using multimodal imaging modalities and to investigate the correlation of FCE and underlying chorioretinal diseases. Methods: This retrospective observational study included 62 eyes from...

Macular Telangiectasia Type 2 -December 2021

Looking at the optical coherence tomography images and fundus autofluorescence images, could you tell the diagnosis in this 39-year-old male patient? Thanks to everyone who showed interest in the section of question of the month...

46. Bietti’s Crystalline Dystrophy

Medical History: A 25-year-old female patient presented with complaint of gradually progressive blurring of vision in both eyes for the past 5 years. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual...

Best Disease-November 2021

Looking at the optical coherence tomography images, could you tell the diagnosis in this young male patient? Thanks to everyone who showed interest in the section of question of the month and answered the question....

Utilizatıon of Spectral Domain Optical Coherence Tomography to Identify Posterior Vitreous Detachment in Patients with Retinal Detachment

Purpose: To compare posterior vitreous detachment (PVD) identification rate between clinical examination versus spectral domain optical coherence tomography in patients with retinal detachment (RD). Methods: Data from the Primary Retinal Detachment Outcomes Study were used for this...

Choriocapillaris ischemia secondary to vortex vein congestion may lead to development of pachychoroid neovasculopathy

Matsumoto and co-workers aimed to evaluate the choroidal congestion in pachychoroid neovasculopathy. In this retrospective case series 100 eyes of 99 treatment-naïve pachychoroid neovasculopathy patients were included. Areas of choriocapillaris flling delay which overlapped...

45. Hypertensive Retinopathy

Medical History: A 60-year-old male patient presented with complaint of blurred vision in both eyes and headache lasting about 1 week. He had a history of coronary artery disease and uncontrolled hypertension. Diabetes mellitus (-) Systemic hypertension...

Persistent Subretinal Fluid Following Successful Retinal Detachment Surgery-October 2021

Looking at the OCT image, could you tell the diagnosis in this patient with a history of successful retinal detachment surgery 3 months ago? Thanks to everyone who showed interest in the section of question...

Temporal inverted ILM flap technique causes fewer vessel density changes in cases with macular hole

Karalezli and co-workers aimed to compare the macular microvasculature differences in cases with idiopathic macular hole after vitrectomy when using internal limiting membrane (ILM) removal or temporal inverted ILM flap technique. A total of...

Preclinical ocular features in patients with Behçet’s disease detected by optical coherence tomography angiography

Objective: The aim of this study was to evaluate the perifoveal and peripapillary microvascular structure in patients with Behçet's disease (BD) without clinically ocular involvement. Methods: Fifty-six eyes of 28 patients with Behçet's disease without clinically ocular...

44. Macular Telangiectasia Type 1

Medical History: A 44-year-old male patient with progressive vision loss in the right eye was examined in our clinic. Diabetes mellitus (-)                                                Systemic hypertension (-) Family history (-) Smoking (-)   Trauma (-) Examination Findings Best corrected visual acuity was...

Myopic Traction Maculopathy (Myopic Foveoschisis)-September 2021

Looking at the optical coherence tomography image, could you tell the diagnosis? Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question telling...

Foveal herniation did not affect the surgical outcomes in patients with ERM

Ozdemir and co-workers aimed to compare the anatomical and visual outcomes of idiopathic epiretinal membrane peeling surgery, with and without foveal herniation. This retrospective, comparative, two-center study included patients exhibiting an idiopathic epiretinal membrane...

Evaluation of the Effects of Silicone Oil on the Macula with Optical Coherence Tomography in Patients with Rhegmatogenous Retinal Detachment

Objectives: The effects of silicone endotamponade duration on the macula were evaluated in patients with rhegmatogenous retinal detachment. Materials and Methods: Sixty-five eyes of 65 cases with rhegmatogenous retinal detachment that underwent pars plana vitrectomy...

43. Macular Telangiectasia Type 2

Medical History: A 68-year-old male patient with progressive vision loss in both eyes was examined in our clinic. Diabetes mellitus  (-)  Systemic hypertension (+) Family history (-) Smoking  (+) Trauma (-) Examination Findings Best corrected visual acuity...

Significant macular alterations in post-COVID-19 patients

Yildiz and co-workers aimed to evaluate to quantify microstructutal alterations in the macula in patients recovered from coronavirus disease 2019 (COVID-19) using optic coherence tomography (OCT). The researchers included patients who recovered from COVID-19...

Laser Induced Maculopathy-August 2021

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, the diagnosis in the young and otherwise healthy male who has blurred...

Microcystic Macular Edema and Cystoid Macular Edema Before and After Epiretinal Membrane Surgery

Purpose: To investigate the types of intraretinal cysts (IRCs) that are associated with epiretinal membranes (ERMs) and to evaluate the effects of each type of IRC on postoperative outcomes. Methods: Retrospective, cross-sectional study design. Patients who underwent...

42. Myopic Traction Maculopathy

Medical History: A 62-year-old female patient with progressive vision loss in both eyes was examined in our clinic. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-)          Examination Findings Best corrected visual...

SubILM Hemorrhage-July 2021

Thanks to everyone who showed interest in the section of question of the month and answered question. In this month's question, identification of the finding on the OCT image in the patient with retinal...

The Fingerprint Sign of the Henle Fiber Layer-June 2021

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, description of the finding on the en face OCT image in the patient...

Evaluation of Retinal Vessel Diameters in Eyes With Active Central Serous Chorioretinopathy

Purpose: To compare the retinal vessel diameters of healthy eyes and active central serous chorioretinopathy (CSC) eyes, and to evaluate possible effect of retinal vessel diameter alterations on the pathogenesis of CSC. Methods: This retrospective...

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