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From Drusen to Type 3 Macular Neovascularization

Purpose: To investigate the imaging features preceding the occurrence of type 3 (T3) macular neovascularization (MNV) using tracked spectral-domain optical coherence tomography (SD-OCT). Method: From a cohort...

68. Reticular Pseudodrusen

Medical History: An 85-year-old female patient presented to our clinic  complaining of decreased vision. Diabetes mellitus (+) Systemic hypertension (+) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual...

Question of the Month-September 2023

   Looking at the multicolor image, fundus autofluorescence image, and optical coherence tomography image, could you tell the diagnosis in this 84-year-old...

Risk of Exudation in Eyes with Non-exudative Polypoidal Choroidal Vasculopathy

Purpose: To investigate the characteristics and natural history of treatment-naïve non-exudative polypoidal choroidal vasculopathy (PCV) and to determine biomarkers predicting exudative conversion. Methods: Patients diagnosed with non-exudative PCV based on indocyanine green angiography (ICGA) and optical coherence...

67. Retinal Pigment Epithelium Tear

Medical History: A 74-year-old female patient with a history of bilateral age related macular degeneration presents complaining of decreased vision in her left eye. Diabetes mellitus (+) Systemic hypertension (+) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual...

Morphological Characteristics and Progression Patterns of Macular Neovascularization-related Atrophy in Eyes with Pathologic Myopia

Purpose: To investigate the development and progression patterns of macular neovascularization (MNV)-related atrophies in eyes with pathologic myopia (PM). Methods: Twenty-seven eyes of 26 patients with MNV followed from its onset to progression to macular...

66. Best Disease Presenting as Subretinal Pigment Epithelium Hyperreflective Lesion on Optical Coherence Tomography

Medical History: An 26-year-old male patient with a history of Best vitelliform macular dystrophy presents for an examination complaining of decreased vision. Diabetes mellitus (-) Systemic hypertension (-) Family history (+) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 8/10...

Subretinal Fluid Associated with Choroidal Nevus-August 2023

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, tell the diagnosis by looking multimodal images in 50-year-old female was desired. The...

Toxic Cholesterol Accumulation Related to Niemann–Pick Disease Type C

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, identify the OCT finding in this young male patient with lysosomal storage...

Complement inhibition for the treatment of geographic atrophy has no effect on functional outcome

Spaide and Vavvas aimed to evaluate available rationale and outcomes of randomized trial results for complement inhibition for geographic atrophy. Data from recently completed randomized trials of complement inhibition, particularly for pegcetacoplan and avacincaptad...

Long-term Progression Pattern of Myopic Tractional Maculopathy: Outcomes and Risk Factors

Purpose: To evaluate the long-term progression pattern of myopic tractional maculopathy and the risk factors. Methods: The prevalence and grade of myopic tractional maculopathy were assessed with optical coherence tomography at enrollment and at the 2-year follow-up....

65. Perifoveal Exudative Vascular Anomalous Complex (PEVAC)

Medical History: A 40-year-old male patient presented with complaint of blurred vision in his right eye. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 9/10 in the right eye and 10/10...

Optic Disk Pit Maculopathy-June 2023

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, tell the diagnosis and identify the OCT finding in this young male...

64. Acquired Vitelliform Lesion in the Setting of Age-Related Macular Degeneration

Medical History: An 84-year-old female patient with a history of dry age related macular degeneration in both eyes presents for an examination complaining of decreased vision. Diabetes mellitus (+) Systemic hypertension (+) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected...

Enlargement of Choroidal Neovascularizatıon before Recurrence after Photodynamic Therapy for Pachychoroid Neovasculopathy

Purpose: To investigate predictors of recurrent exudation in choroidal neovascularization (CNV) of pachychoroid neovasculopathy (PNV) after photodynamic therapy (PDT). Methods: Consecutive, treatment-naïve, symptomatic patients with PNV with subfoveal retinal fluid (SRF) treated with PDT and followed for...

Arteriovenous Malformation- May 2023

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, identify the OCT finding in patient with Wyburn-Mason Syndrome was desired. The answer...

Photobiomodulation therapy for large soft drusen and drusenoid pigment epithelial detachment in age-related macular degeneration: a single-center prospective pilot study

Purpose: To evaluate visual acuity and morphologic changes after photobiomodulation (PBM) for patients affected with large soft drusen and/or drusenoid pigment epithelial detachment (dPED) associated to dry age-related macular degeneration (AMD). Method: Twenty eyes with...

63. Choroidal Macrovessel

Medical History: A 67-year-female patient presented to our clinic for an annual examination. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 10/10 in the right eye and 10/10 in the left...

Poppers Maculopathy-April 2023

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, tell the diagnosis by looking OCT and multicolor images was desired. The answer...

Subretinal Fluid Associated with Drusenoid Pigment Epithelial Detachment

Purpose: To analyze the clinical characteristics of drusenoid pigment epithelial detachment (PED) with subretinal fluid (SRF) and to evaluate the impact of SRF on the long-term visual and anatomical outcomes. Methods: Forty-seven eyes with drusenoid...

62. Isolated Foveal Hypoplasia

Medical History: A 45-year-male patient presented to our clinic for an annual examination. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 9/10 in the right eye and 9/10 in the left...

Autosomal Recessive Best Disease-March 2023

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, tell the diagnosis by looking OCT and FAF images was desired. The answer...

Increasing Evidence for the Safety of Fovea-Involving Half-dose Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

Purpose: A retrospective study was performed with data from the prospective randomized controlled trials, PLACE and SPECTRA, assessing the risk of foveal atrophy and the likelihood of structural and functional improvement on optical coherence tomography,...

61. Choroidal Rupture

Medical History: A 20-year-old male patient presented with a complaint of decreased vision after blunt trauma in his left eye. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (+) Examination Findings Best corrected visual acuity was 10/10 in the...

TYPE-3 NV (RAP)-February 2023

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, tell the diagnosis by looking OCT and OCTA images was desired. The answer to the question is...

60. Subretinal Fluid Associated with Choroidal Nevus

Medical History: A 50-year-old female patient presented with complaint of vision loss in the left eye. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 10/10 in the right eye and 5/10...

Predisposing characteristics of optical coherence tomography for patients with persistent subretinal fluid after successful repair of rhegmatogenous retinal detachment

Purpose: To investigate the predisposing clinical parameters and characteristics of fundus imaging of patients with persistent subretinal fluid (PSF) after successful repair of rhegmatogenous retinal detachment. Methods: A retrospective study recruiting 57 patients was conducted....

Henle Fiber Layer Hemorrhage-January 2023

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, identify the OCT finding in patient with branch retinal vein occlusion was desired. The answer to the...

Vitrectomy for myopic traction maculopathy may accelerate the progression of myopic (atrophic) maculopathy

Park and co-workers aimed to compare the progression of myopic maculopathy with or without vitrectomy in patients with myopic traction maculopathy. Seventy-seven eyes with MTM were classified into either the observation group (n =...

Use of Optical Coherence Tomography in Detecting Retinal Tears in Acute, Symptomatic Posterior Vitreous Detachment

Purpose: To evaluate the association of posterior vitreous opacities (PVO) on optical coherence tomography (OCT) with retinal tears identified on exam, in patients with acute, symptomatic posterior vitreous detachment (PVD). Method: Data was retrospectively collected...

59. Accidental Macular Injury Induced by Cosmetic Laser

Medical History: A 25-year-old female patient presented with complaint of vision loss in the right eye. She was accidentally exposed to a cosmetic laser. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity...

Choroidal Rift-December 2022

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, identify the novel OCT finding in eyes with chronic central serous chorioretinopathy was desired. The answer to...

Focal Choroidal Thickness Hemodynamıcs as a Sign of Macular Neovascularizatıon Activity in Pathologic Myopia

Purpose: To analyze the relationship between a focal increase of choroidal thickness (ChT) and exudative activity of macular neovascularization (MNV) secondary to pathologic myopia. Methods: Retrospective analysis including eyes with pathologic myopia presenting with a focally increased...

58. Serous Retinal Detachment Associated with Dome-Shaped Macula

Medical History: A 50-year-old female patient presented with complaint of vision loss in the right eye. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 5/10 in the right eye and 10/10...

57. Exophytic Juxtapapillary Retinal Capillary Hemangioma

Medical History: A 60-year-old female patient presented with complaint of floaters in the right eye. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 10/10 in the right eye and 10/10 in...

BRAF/MEK Inhibitor-Associated Retinopathy-November 2022

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, determine the diagnosis by looking OCT and IR images in a male patient with...

Combined Hamartoma of the Retina and Retinal Pigment Epithelium at Pediatric Age: Surgical versus Conservative Approach

Purpose: To report outcomes of pediatric patients with combined hamartoma of the retina and the retina pigment epithelium (CHRRPE) followed up conservatively or after pars plana vitrectomy (PPV). Methods: This retrospective multicenter study included sixty-two...

Bacillary Layer Detachment and Serous Retinal Detachment- October 2022

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, determine the diagnosis by looking OCT image in a 16-year-old male patient was asked. The answer...

Optical coherence tomography angiography diagnosed decreased deep capillary plexus vessel density values in patients with preeclampsia

Özcan and co-workers investigated microvascular changes in the retina and optic disk by comparing the optical coherence tomography angiography findings in preeclamptic patients with those in control groups and also evaluated the preeclamptic patients...

Conventional internal limiting membrane peeling versus inverted flap for small-to-medium idiopathic macular hole: a randomized trial

Purpose: To compare conventional internal limiting membrane (ILM) peeling versus inverted flap technique in small-to-medium idiopathic macular hole. Methods: Eyes with ≤400 microns Idiopathic macular holes were randomized into the conventional ILM peeling group (25 eyes) and...

56. Myelinated Retinal Nerve Fiber Layer

Medical History: A 41-year-female patient presented to our clinic for an annual examination. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 10/10 in the right eye and 10/10 in the left...

Effect of Oral Carbonic Anhydrase İnhibitor on Cystoid Macular Edema Associated with Retinitis Pigmentosa: An OCT and OCT Angiography Study

Purpose: To investigate the factors associated with visual improvement in response to oral carbonic anhydrase inhibitors (CAIs) and the occurrence of microvascular changes in patients with retinitis pigmentosa-associated cystoid macular edema (RP-CME). Methods: This retrospective cohort study...

Drainage retinotomy is a risk factor for surgical failure after pars plana vitrectomy in patıents with primary uncomplicated rhegmatogenous retinal detachment

Hiromi and co-workers aimed to identify risk factors for recurrent retinal detachment after uncomplicated pars plana vitrectomy (PPV) in patients with primary rhegmatogenous retinal detachment (RRD). They analyzed 519 eyes of 509 patients who...

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