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Effect of Oral Carbonic Anhydrase İnhibitor on Cystoid Macular Edema Associated with Retinitis Pigmentosa: An OCT and OCT Angiography Study

Purpose: To investigate the factors associated with visual improvement in response to oral carbonic anhydrase inhibitors (CAIs) and the occurrence of microvascular changes in patients...

Drainage retinotomy is a risk factor for surgical failure after pars plana vitrectomy in patıents with primary uncomplicated rhegmatogenous retinal detachment

Hiromi and co-workers aimed to identify risk factors for recurrent retinal detachment after uncomplicated pars plana vitrectomy (PPV) in patients with primary rhegmatogenous retinal...

Question of the Month-September 2022

Could you tell the diagnosis by looking these images in a 32-year-old male patient? OCT Club will present the book ‘Istanbul City of Forgetting and Remembering’ to...

55. Choroidal Nevus

Medical History: A 60-year-old female patient presented to our clinic for an annual examination. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 10/10 in the right eye and 10/10 in the...

Retinal Pigment Epithelium Tear-August 2022

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, determine the diagnosis by looking OCT, IR images in patient with diagnosis of amd was...

Question of the Month- August 2022

Could you tell the diagnosis by looking this image in a patient with diagnosis of age-related macular degeneration ? OCTCLUB will present the book 'Bosphorus The Ultimate Guide' to one person with correct answer to...

54. Choroidal neovascular membrane secondary to pattern dystrophy simulating fundus flavimaculatus

Medical History: A 60-year-old male patient presented to our clinic with a three-day history of vision loss his right eye. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 6/10 in the...

People with proliferative diabetic retinopathy treated with multispot pattern laser had higher risk of progression than those receiving the standard single-spot laser

Perais and co-workers aimed to determine effects of baseline characteristics and laser type performed on outcomes in people with proliferative diabetic retinopathy undergoing panretinal photocoagulation. One hundred and fourteen patients (135 eyes) were included....

Imaging the vitreous with a Novel Boosted Optical Coherence Tomography Technique: Vitreous Degeneration and Cisterns

Purpose: To evaluate the degenerative findings including cistern formation in the premacular vitreous using optical coherence tomography. Methods: A novel enhanced vitreous imaging method by which four A-scans at each position were averaged before the...

Macular Telengiectasia Type-2 and Central Serous Chorioretinopathy – July 2022

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, determine the diagnosis by looking OCT, FAF and IR images in a 52-year-old male...

53. Vitelliform Macular Lesion Associated with Cuticular Drusen

Medical History: A 45-year-old male patient presented with complaint of blurry vision in both eyes for the past 3 years.  Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 7/10 in the...

Laser photocoagulation is an effective treatment to prevent retinal detachment in patients with acute retinal necrosis

Chen and co-workers aimed to evaluate whether prophylactic laser is effective for retinal detachment following acute retinal necrosis. PubMed, Embase and Cochrane databases were searched, and the retrieved records were screened. 14 studies with a...

Pars Plana Vitrectomy with and without ILM-peeling for Diabetic Patients with Macula Involved Tractional Retinal Detachment

Purpose: To evaluate the effect of internal limiting membrane (ILM) peeling on anatomical and functional results in pars plana vitrectomy (PPV) performed eyes with tractional retinal detachment affecting the macula due to diabetes mellitus (DM). Methods: Patients...

Dry Age Related Macular Degeneration-Regression of Drusenoid Pigment Epithelium Detachment- June 2022

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, determine the diagnosis by looking OCT,IR and FAF images in a 78-year-old...

52. Valsalva Retinopathy

Medical History: A 41-year-old male patient presented with complaint of sudden painless loss of vision in the left eye after performing a Valsalva-type maneuver. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual...

Predictive factors of spontaneous release of vitreomacular traction: a systematic review and meta-analysis

Purpose: To review predictive factors of spontaneous vitreomacular traction (VMT) release. Methods: A systematic literature search was performed on Ovid MEDLINE, Embase, and Cochrane Library. Studies comparing spontaneously released VMT to persistent VMT were included....

AKST4290 treatment is associated with improved visual acuity scores in patients with neovascular age-related macular degeneration

Stewart and co-workers evaluated the safety and therapeutic effects of orally administered AKST4290 in treatment-naive patients with neovascular age-related macular degeneration. In this prospective, multicenter, open-label Phase 2a pilot clinical study, 30 patients with...

Transcorneal Electrical Stimulation Therapy May Have a Stabilization Effect on Multifocal Electroretinography for Patients with Retinitis Pigmentosa

Dizdar Yigit and co-workers aimed to assesses the effects of transcorneal electrical stimulation on several objective and subjective measures of visual function in retinitis pigmentosa. Transcorneal electrical stimulation was applied monocularly, 30 minutes/week for...

Differences in long-term progression of atrophy between neovascular and non-neovascular age-related macular degeneration

Purpose: To compare enlargement rates over 5 years of follow-up in geographic atrophy (GA) versus macular atrophy (MA) associated with macular neovascularization (MNV). Design: Retrospective, longitudinal comparative case series of age-related macular degeneration (AMD)...

51. Choroideremia

Medical History: A 39-year-old male patient presented with complaint of gradually progressive loss of night vision. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual acuity was 9/10 in the right eye and...

Doyne Honeycomb Retinal Dystrophy-May 2022

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, determine the diagnosis by looking OCT, IR and OCTA images in a 35-year-old male...

No difference in the incidence of age-related macular degeneration between statin users and nonusers

Age-related macular degeneration shares many of the same risk factors with atherosclerosis. There is a postulated role of lipid-lowering agents in preventing age-related macular degeneration. Through this meta-analysis, Eshtiaghi and co-workers demonstrate no significant...

Efficacy of Half-Dose Photodynamic Therapy Versus High-Density Subthreshold Micropulse Laser for Treating Pigment Epithelial Detachments in Chronic Central Serous Chorioretinopathy

Purpose: Comparing the effect of half-dose photodynamic therapy and high-density subthreshold micropulse laser treatment on retinal pigment epithelial detachments (PEDs) in chronic central serous chorioretinopathy. Methods: This study included data from the PLACE trial, a...

50. Choroidal Neovascularization Associated with Angioid Streaks in Pseudoxanthoma Elasticum

Medical History: A 27-year-old female patient presented with complaint of blurry vision in the right eye for the past 3 weeks.   Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Small yellowish papules coalescing into...

The Pearl Necklace Sign-April 2022

Thanks to everyone who showed interest in the section of question of the month and answered the question. In this month's question, describe the OCT finding in a patient with disciform scar and cystoid macular degeneration was asked. The...

Hyper-reflective oval deposits – March 2022

The OCT image of a patient who developed posterior uveitis is shown. Could you determine the diagnosis and describe the OCT findings indicated by arrows of this patient? Thanks to everyone who showed interest in...

Subjects with central serous chorioretinopathy are at increased risk of exudative age-related macular degeneration

Lee and co-workers aimed to estimate the risk of incident age-related macular degeneration (AMD) in patients with central serous chorioretinopathy (CSC). During a recent 5-year study period, 36,053 patients were identified as having incident...

Predictors of Retinal Pigment Epithelium Tear Development After Treatment for Neovascular Age-Related Macular Degeneration Usıng Swept-Source Optical Coherence Tomography Angiography

Purpose: To investigate the predictors of retinal pigment epithelium (RPE) tear development after treatment for neovascular age-related macular degeneration (AMD) using swept-source optical coherence tomography angiography (OCTA). Methods: This prospective study included 152 treatment-naïve eyes...

49. Vascularized serous pigment epithelial detachment in age-related macular degeneration

Medical History: A 75-year-old female patient presented with complaint of gradually progressive blurring of vision in the left eye for the past 3 months.   Diabetes mellitus (+) Systemic hypertension (+)   Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected...

Retinal age as a predictive biomarker for mortality risk

Zhu and co-workers aimed to develop a deep learning (DL) model that predicts age from fundus images (retinal age) and to investigate the association between retinal age gap (retinal age predicted by deep learning...

Hyperreflective foci as important prognostic indicators of progression of retınitis pigmentosa

Purpose: To investigate the presence and clinical relevance of hyperreflective foci (HRFs) in retinitis pigmentosa. Methods: Seventy seven retinitis pigmentosa cases were retrospectively reviewed. The 10-mm wide cross-line macular scans in optical coherence tomography were acquired. Hyperreflective...

Nebulous Pattern Vitritis-February 2022

The OCT image of a patient who developed cytomegalovirus retinitis is shown. Could you describe the OCT findings indicated by asterisk and arrows of this patient? Thanks to everyone who showed interest in the section...

Alport Syndrome-January 2022

Looking at the optical coherence tomography images and infrared reflectance images, could you tell the diagnosis in this 42-year-old female patient with the diagnosis of chronic kidney disease? Thanks to everyone who showed interest in...

47. Very Late Onset Irvine-Gass Syndrome

Medical History: A 68-year-old female patient presented with complaint of blurry vision in her left eye for 2 months. In her history; 8 years ago she had bilateral cataract surgery. Diabetes mellitus  (+) Systemic hypertension (+) Family history...

Intraretinal fluid may be associated with good visual acuity in Type 3 macular neovascularization

Sharma and co-workers aimed to analyze the effect of fluid on visual acuity in cases of Type 3 macular neovascularization. This multicentric, retrospective cohort study included eyes with treatment-naïve Type 3 macular neovascularization. Analysis...

Peripapillary pachychoroid syndrome: New Insights

Purpose: Available literature on peripapillary pachychoroid syndrome (PPS) is very limited. The purpose of this study is to evaluate features of PPS using multimodal imaging and shed further light on this entity. Methods: This is...

Macular Hole Closure Without Endotamponade Application

Stopa and co-workers describe an alternative vitreoretinal technique that allows for the macular hole closure without filling the vitreous cavity with gas. The patients underwent the formation of viscoelastic-assisted temporal internal limiting membrane flap...

Correlation between focal choroidal excavation and underlying retinochoroidal disease: A pathological hypothesis from clinical observation

Purpose: To evaluate focal choroidal excavation (FCE) in eyes with various diseases using multimodal imaging modalities and to investigate the correlation of FCE and underlying chorioretinal diseases. Methods: This retrospective observational study included 62 eyes from...

Macular Telangiectasia Type 2 -December 2021

Looking at the optical coherence tomography images and fundus autofluorescence images, could you tell the diagnosis in this 39-year-old male patient? Thanks to everyone who showed interest in the section of question of the month...

46. Bietti’s Crystalline Dystrophy

Medical History: A 25-year-old female patient presented with complaint of gradually progressive blurring of vision in both eyes for the past 5 years. Diabetes mellitus (-) Systemic hypertension (-) Family history (-) Smoking (-) Trauma (-) Examination Findings Best corrected visual...

Best Disease-November 2021

Looking at the optical coherence tomography images, could you tell the diagnosis in this young male patient? Thanks to everyone who showed interest in the section of question of the month and answered the question....

Utilizatıon of Spectral Domain Optical Coherence Tomography to Identify Posterior Vitreous Detachment in Patients with Retinal Detachment

Purpose: To compare posterior vitreous detachment (PVD) identification rate between clinical examination versus spectral domain optical coherence tomography in patients with retinal detachment (RD). Methods: Data from the Primary Retinal Detachment Outcomes Study were used for this...

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