Purpose: To analyze the relationship between a focal increase of choroidal thickness (ChT) and exudative activity of macular neovascularization (MNV) secondary to pathologic myopia.
Methods: Retrospective analysis including eyes with pathologic myopia presenting with a focally increased ChT underneath active MNV. All patients included were treated, and ChT was measured before and after each intravitreal injection by two experienced ophthalmologists.
Results: Fifty-two eyes of 52 patients with myopic MNV (19 men and 33 women) were included in this analysis. ChT at T-1 averaged 51.09 ± 33.56 μ m, whereas at the time of MNV activation (T0), ChT was significantly thicker: 85.11 ± 43.99 μ m ( P < 0.001). After a single intravitreal injection, the ChT significantly decreased to 53.23 ± 34.15 μ m ( P < 0.001).
Conclusion: This study showed that focal ChT variations may be considered an interesting corollary sign of MNV in high myopic patients, indicating the activity of myopic neovascularization.
Amoroso F, Miere A, El Matri K, et al. Focal Choroidal Thickness Hemodynamics as a Sign of Macular Neovascularization Activity in Pathologic Myopia. Retina 2022;42:2321-2325. https://pubmed.ncbi.nlm.nih.gov/36161985/