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Metformin use is associated with reduced odds of developing neovascular age related macular degeneration.

Khanna and co-workers aimed to investigate if metformin use reduces the odds of developing new neovascular AMD (nAMD). This is a case–control study of...

Complement inhibition for the treatment of geographic atrophy has no effect on functional outcome

Spaide and Vavvas aimed to evaluate available rationale and outcomes of randomized trial results for complement inhibition for geographic atrophy. Data from recently completed...

Vitrectomy for myopic traction maculopathy may accelerate the progression of myopic (atrophic) maculopathy

Park and co-workers aimed to compare the progression of myopic maculopathy with or without vitrectomy in patients with myopic traction maculopathy. Seventy-seven eyes with...

Optical coherence tomography angiography diagnosed decreased deep capillary plexus vessel density values in patients with preeclampsia

Özcan and co-workers investigated microvascular changes in the retina and optic disk by comparing the optical coherence tomography angiography findings in preeclamptic patients with those in control groups and also evaluated the preeclamptic patients...

Drainage retinotomy is a risk factor for surgical failure after pars plana vitrectomy in patıents with primary uncomplicated rhegmatogenous retinal detachment

Hiromi and co-workers aimed to identify risk factors for recurrent retinal detachment after uncomplicated pars plana vitrectomy (PPV) in patients with primary rhegmatogenous retinal detachment (RRD). They analyzed 519 eyes of 509 patients who...

People with proliferative diabetic retinopathy treated with multispot pattern laser had higher risk of progression than those receiving the standard single-spot laser

Perais and co-workers aimed to determine effects of baseline characteristics and laser type performed on outcomes in people with proliferative diabetic retinopathy undergoing panretinal photocoagulation. One hundred and fourteen patients (135 eyes) were included....

Laser photocoagulation is an effective treatment to prevent retinal detachment in patients with acute retinal necrosis

Chen and co-workers aimed to evaluate whether prophylactic laser is effective for retinal detachment following acute retinal necrosis. PubMed, Embase and Cochrane databases were searched, and the retrieved records were screened. 14 studies with a...

AKST4290 treatment is associated with improved visual acuity scores in patients with neovascular age-related macular degeneration

Stewart and co-workers evaluated the safety and therapeutic effects of orally administered AKST4290 in treatment-naive patients with neovascular age-related macular degeneration. In this prospective, multicenter, open-label Phase 2a pilot clinical study, 30 patients with...

Transcorneal Electrical Stimulation Therapy May Have a Stabilization Effect on Multifocal Electroretinography for Patients with Retinitis Pigmentosa

Dizdar Yigit and co-workers aimed to assesses the effects of transcorneal electrical stimulation on several objective and subjective measures of visual function in retinitis pigmentosa. Transcorneal electrical stimulation was applied monocularly, 30 minutes/week for...

No difference in the incidence of age-related macular degeneration between statin users and nonusers

Age-related macular degeneration shares many of the same risk factors with atherosclerosis. There is a postulated role of lipid-lowering agents in preventing age-related macular degeneration. Through this meta-analysis, Eshtiaghi and co-workers demonstrate no significant...

Subjects with central serous chorioretinopathy are at increased risk of exudative age-related macular degeneration

Lee and co-workers aimed to estimate the risk of incident age-related macular degeneration (AMD) in patients with central serous chorioretinopathy (CSC). During a recent 5-year study period, 36,053 patients were identified as having incident...

Retinal age as a predictive biomarker for mortality risk

Zhu and co-workers aimed to develop a deep learning (DL) model that predicts age from fundus images (retinal age) and to investigate the association between retinal age gap (retinal age predicted by deep learning...

Intraretinal fluid may be associated with good visual acuity in Type 3 macular neovascularization

Sharma and co-workers aimed to analyze the effect of fluid on visual acuity in cases of Type 3 macular neovascularization. This multicentric, retrospective cohort study included eyes with treatment-naïve Type 3 macular neovascularization. Analysis...

Macular Hole Closure Without Endotamponade Application

Stopa and co-workers describe an alternative vitreoretinal technique that allows for the macular hole closure without filling the vitreous cavity with gas. The patients underwent the formation of viscoelastic-assisted temporal internal limiting membrane flap...

Choriocapillaris ischemia secondary to vortex vein congestion may lead to development of pachychoroid neovasculopathy

Matsumoto and co-workers aimed to evaluate the choroidal congestion in pachychoroid neovasculopathy. In this retrospective case series 100 eyes of 99 treatment-naïve pachychoroid neovasculopathy patients were included. Areas of choriocapillaris flling delay which overlapped...

Temporal inverted ILM flap technique causes fewer vessel density changes in cases with macular hole

Karalezli and co-workers aimed to compare the macular microvasculature differences in cases with idiopathic macular hole after vitrectomy when using internal limiting membrane (ILM) removal or temporal inverted ILM flap technique. A total of...

Foveal herniation did not affect the surgical outcomes in patients with ERM

Ozdemir and co-workers aimed to compare the anatomical and visual outcomes of idiopathic epiretinal membrane peeling surgery, with and without foveal herniation. This retrospective, comparative, two-center study included patients exhibiting an idiopathic epiretinal membrane...

Significant macular alterations in post-COVID-19 patients

Yildiz and co-workers aimed to evaluate to quantify microstructutal alterations in the macula in patients recovered from coronavirus disease 2019 (COVID-19) using optic coherence tomography (OCT). The researchers included patients who recovered from COVID-19...

Preoperative macular domed contour in eyes with ERM predicted better visual gain after vitrectomy

Zayer and co-workers aimed to evaluate macular features on preoperative ocular coherence tomography (OCT) as indicators of postoperative visual gain following vitrectomy for epiretinal membrane (ERM). The researchers included 66 patients that underwent vitrectomy...

Morphological en face OCT patterns in eyes with uveitic macular edema

Karti  and co-workers aimed to elucidate the en face optical coherence tomography (OCT) patterns of macular edema in eyes with angiographically documented uveitic macular edema (UME). The researchers included thirty-nine eyes of 29 patients...

Peripheral cystoid degeneration may be associated with the pathogenesis of rhegmatogenous retinal detachment

Nishitsuka and co-workers examined the peripheral vitreous and retina in patients with rhegmatogenous retinal detachment (RRD) using intraoperative optical coherence tomography (OCT). The researchers retrospectively included 50 eyes of 50 patients that underwent...

New OCT grading system for macula-off rhegmatogenous retinal detachment

Baden KT and co-workers introduced a new grading system for determining the influence and extent of macular detachment seen in preoperative optical coherence tomography (OCT) evaluation in relation to the postoperative visual outcome and...

May neurosensory retina provide a window into pathology of the central nervous system?

Some patients with Parkinson disease present with atypical features, complicating the diagnostic process. There is a need for noninvasive biomarkers that may improve our ability not only to diagnose Parkinson disease, but also perhaps...

Self-examination OCT for patients with macular diseases

Frequent OCT controls are needed to monitor disease activity in anti-VEGF therapy under real-life conditions. This poses a significant burden and may promote non-adherence. OCT home-monitoring could alleviate this burden and lead to earlier...

Point-of-care diagnostics, telemedicine and remote monitoring

Advancing the OCT technology in terms of portability and self-examination improves the accessibility and field of application. The portability of all these devices has allowed for imaging of patients in different positions and beyond...

The International OCT and OCT Angiography Meeting begins in Rome.

The 'International OCT and OCT Angiography (ICOOR 2020)' meeting, which is held every year in Rome and will be held for the eighth time this year, will be held in virtual environment on 18-19...

Virtual Imaging Symposium

The 18th International SPECTRALIS® Symposium (ISS) will be held virtually for the first time as part of the International Imaging Symposium on October 30-31, 2020 due to the current situation. The scientific program includes...

New OCT2 platform started to be used at the International Space Base

OCT2, the new OCT platform developed by Heidelberg Engineering, was put into use at the International Space Base.  Spectralis (Heidelberg Engineering), the first OCT device to go to space, has achieved a new first....

Scientific studies on self-examination with the home OCT started

Notal Vision, reported that the first research with a home optical coherence tomography remote monitoring device is started. This study will evaluate the daily retinal fluid changes in patients receiving anti-VEGF therapy for age-related...

Can OCT-Angiography help diagnose early stages of Alzheimer’s disease?

In the study conducted by Elizabeth O'Bryhim et al. from Washington University on preclinical Alzheimer's patients, significant retinal vascular changes have been detected with OCT-Angiography. It was shown that the foveal avascular zone was...

Videos of OCTCLUB 2018 meeting presentations are posted on octclub.org.

https://www.youtube.com/playlist?list=PLqToM8gdSkgbRg1GYBMpyQhucDnmv8lRV

OCT-A shows reduction in retinal vessels in migraine with aura

Melinda et al. found in their study that OCT-angio (OCT-A) precisely showed the foveal and peripapillary vascular reduction in migraine patients with aura.  The lack of vascular changes in patients with migraine without aura...

Evaluation of retinal vascular density in MS patients with OCT-Angiography

OCT-Angiography can be used to detect decreased retinal vascular density in multiple sclerosis patients. In the study conducted by Roberta Lanzillo et al. from the University of Naples, was found that there was a...

OCT can be an important biomarker in Alzheimer’s Disease.

Recently, some changes detected in the retina are accepted as a biomarker for neurodegenerative diseases.  It has been proposed  that changes in retinal thickness determined by optical coherence tomography (OCT) in patients with Alzheimer's...

Premature babies have smaller foveal avascular zone.

In the study conducted by Falavarjani et al. from the University of California with OCT-angiography in preterm babies, was shown that the foveal avascular zone (FAZ)  was absent or significantly smaller. Foveal avascular zone...

Perifoveal microvascular changes in patients with active Behçet’s disease

OCT-angiography (OCT-A) was found to be more successful than fluorescein angiography (FA) in evaluating perifoveal microvascular changes in patients with active Behçet disease. In the study of Khairallah et al. including 44 eyes with...

The retinal nerve fiber layer gets thinner in fibromyalgia

Garcia-Martin et al., from the University of Zaragoza, reported that fibromyalgia causes thinning of the retinal nerve fiber layer. In an observational, prospective study performed on 116 fibromyalgia patients and 144 controls, retinal nerve...

Vigabatrin toxicity in infancy causes retinal defects in childhood.

Vigabatrin is a drug commonly used in pediatric epilepsies in recent years. Pediatric neurologists state that they can successfully control many cases of resistant epilepsy with this drug. However, the drug has a major...

OCT images taken in gas-filled eyes

On OCT images taken in gas-filled eyes, anatomical structures were shown to be significantly smaller than their actual size. In their interesting study, Yamashita et al. from Kagoshima University showed that on the OCT...

Choroidal thickness in patients with Graves’ orbitopathy

Graves orbitapatili hastalarda koroidin daha kalın olduğu tespit edildi. Ozkan et al., from Kocaeli University Medical School, Department of Ophthalmlology, found that the choroid was thicker in patients with Graves' orbitopathy. Thirty-one patients with mild...

Istanbul Retina 2016 Meeting was held on 15-16 April.

Istanbul Retina 2016 meeting, which also included the 3rd OCT Club and the 2nd Vitrectomy Club sessions, was held in Istanbul on 15-16 April 2016. In the two-day meeting where 60 speakers took part,...

The translation of the book “Optical Coherence Tomography in Eye Diseases” has been published.

Dünyanın en çok satılan OCT kitaplarından biri olan “Göz Hastalıklarında Optik Koherens Tomografi” adlı kitabın çeviri basımı Reaktif Basımevi tarafından yayınlandı. The translation edition of the book "Optical Coherence Tomography in Eye Diseases", one of...

Does exercise affect choroidal thickness?

Egzersiz koroid kalınlığını etkiler mi? Sayın et al. conducted a study on 19 healthy individuals and measured the choroidal thickness of the participants with EDI-OCT after using a 10-minute ergometer exercise bike. Measurements were performed...

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