Choriocapillaris ischemia secondary to vortex vein congestion may lead to development of pachychoroid neovasculopathy

Matsumoto and co-workers aimed to evaluate the choroidal congestion in pachychoroid neovasculopathy. In this retrospective case series 100 eyes of 99 treatment-naïve pachychoroid neovasculopathy patients were included. Areas of choriocapillaris flling delay which overlapped with dilated outer choroidal vessels and choroidal neovascularization were assessed. On indocyanine green angiography, all eyes showed choriocapillaris flling delay in the early phase. The areas of choriocapillaris flling delay overlapped extensively with that of dilated outer choroidal vessels. All eyes showed choroidal neovascularization localized within the sites of choriocapillaris flling delay. Matsumoto and co-workers cocluded that chronic choriocapillaris ischemia secondary to vortex vein congestion may lead to choroidal neovascularization development in eyes with pachychoroid neovasculopathy.

Matsumoto, H., Hoshino, J., Mukai, R. et al. Chronic choriocapillaris ischemia in dilated vortex vein region in pachychoroid neovasculopathy. Sci Rep. 2021;11(1):16274.



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