Age-related macular degeneration shares many of the same risk factors with atherosclerosis. There is a postulated role of lipid-lowering agents in preventing age-related macular degeneration. Through this meta-analysis, Eshtiaghi and co-workers demonstrate no significant difference in the incidence of early or late age-related macular degeneration between statin users and nonusers. Furthermore, in patients with existing AMD, statin use had no significant influence on the subsequent development of choroidal neovascularization or geographic atrophy.
Eshtiaghi A, Popovic MM, Sothivannan A, Muni RH, Kertes PJ. Statin Use and the Incidence of Age-Related Macular Degeneration: A Meta-Analysis. Retina. 2022;42:643-652. https://pubmed.ncbi.nlm.nih.gov/34983903/