Karalezli and co-workers aimed to compare the macular microvasculature differences in cases with idiopathic macular hole after vitrectomy when using internal limiting membrane (ILM) removal or temporal inverted ILM flap technique. A total of 34 patients were included, of whom 20 were treated vitrectomy with ILM removal (group 1), and 14 were treated with inverted ILM flap technique (group 2). The OCTA (RTVue; Optovue, Fremont, CA) ) parameters were evaluated at baseline and 6 months follow-up. The mean post-operative nasal vessel density of the deep capillary plexus was lower in group 1 than in group 2 (p = 0.005 and p = 0.03 for parafovea and perifovea, respectively). Paranasal and perinasal inner retinal thickness were significantly thinner in group 1 than in group 2 (p < 0.001, p < 0.001).
Karalezli and co-workers concluded that temporal inverted ILM flap technique causes fewer vessel density changes when compared to complete ILM removal.
Karalezli A, Kaderli ST, Sul S. Macular microvasculature differences in patients with macular hole after vitrectomy with internal limiting membrane removal or single-layered temporal inverted flap technique. Eye (Lond). 2021;35(10):2746-2753. https://pubmed.ncbi.nlm.nih.gov/33235343/