Lee and co-workers aimed to estimate the risk of incident age-related macular degeneration (AMD) in patients with central serous chorioretinopathy (CSC). During a recent 5-year study period, 36,053 patients were identified as having incident CSC. The annual incidence in the latest year was 19.61 per 100,000 people. A total of 11,492 patients were included in the study group and 22,984 in the non-CSC group. The CSC and non-CSC groups included 166 (1.44%) and 73 (0.32%) cases of exudative AMD, respectively. The risk of exudative AMD was significantly higher in the CSC group than the non-CSC group (P < 0.001). Lee and co-workers cocluded that subjects with CSC are at increased risk of exudative AMD. This evidence supports a possible link between CSC and exudative AMD.
Lee JY, Bae K. Risk of exudative age-related macular degeneration in patients with central serous chorioretinopathy: A nationwide cohort study. Retina. 2022 Jan 20. https://pubmed.ncbi.nlm.nih.gov/35067609/