Subretinal Hyperreflective Material-November 2020


Could you determine the diagnosis and describe the finding marked with asterisk at the OCT image of an elderly patient who had sub RPE infiltrates on fundus examination and was followed up with a diagnosis of posterior uveitis?


The answer to the question is ‘’Primary Vitreoretinal Lymphoma/Subretinal Hyperreflective Material’’. As a result of the lottery drawn among those who answered the question correctly, Mr. Dr. Yigit Caglar Bozdogan won this month’s book prize. Congratulations to him.

Primary vitreoretinal lymphoma is a rare malignancy. Primary vitreoretinal lymphoma is a subtype of diffuse large B-cell lymphomas of the central nervous system and is usually of B lymphocyte origin.  “Subretinal Hyperreflective Material” seen on OCT imaging is a very typical finding for primary vitreoretinal lymphoma.



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