Chen and co-workers aimed to compare the anatomical and functional outcomes of the inverted flap technique versus conventional internal limited membrane (ILM) peeling in large idiopathic full-thickness macular holes <650 µm. Sixty-nine eyes of 69 patients who underwent the IFT (n = 32, Group A) or ILM peeling (n = 37, Group B) were included.They reported that the inverted flap technique is not a suitable option for repairing large macular holes <650 µm in diameter. This study demonstrated poorer external limiting membrane and visual recovery in the inverted flap group than the conventional internal limited membrane peeling group.
Chen J, Tao J, Zhang Y. The inverted internal limiting membrane flap technique is not recommended for the treatment of large macular holes smaller than 650 µm. Retina. 2024 Aug 14;44(12):2086–90. https://pubmed.ncbi.nlm.nih.gov/39151201/
